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Covid vacc and raised PSA

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User
Posted 11 Oct 2021 at 23:54

My OH had PSA readings:

2019 - 4.4

March 2020 - 5.1

19th April 2021 - 8.3 (when all this started with follow up MRI)

He had his 2nd Pfizer jab 18th April 2021.

Could this possibly be part of the reason for the big jump? I know it doesn’t really matter now as he had the tests and it was PCa, but definitely interesting if that contributed to the rise.

User
Posted 12 Oct 2021 at 01:09

Elaine that is quite interesting, that the jab and test were so close. I don't think any research has been done in to this other than what we have observed on this forum. Most of the reports here were from people on HT and the gap between jab and PSA test was of the order of weeks, rise was about 10%. Your OH had a fully functioning prostate and a one day gap, well we have no comparison to that. No one knew at the time, but with hind sight I would say that test was unreliable.

Dave

User
Posted 12 Oct 2021 at 07:23

Yes I guess worth thinking about for anyone who has their booster vaccine and then PSA check coming up. I read an article with a doctor in Florida saying he had seen patterns of psa rise up to 6 weeks after jab and then lowered after this time (how reliable I’m not sure?) We’ll never know if this was the case for us now as OH has started HT anyway and like I say doesn’t really make much difference at this stage. Thanks for the reply Dave.

User
Posted 19 Oct 2021 at 21:22

PSA Levels

1/27/2017 - 0.59

12/4/2018 - 0.74

7/13/2020 - 0.53

10/18/2021 - 1st Pfizer Shot

10/19/2021 - 1.180

User
Posted 19 Oct 2021 at 23:07

Thank you John, big jump right after jab. Please post again after your next test, it will be interesting to see if it comes back down. This could be important for people on active surveillance, at least we now have half the story. If it comes down we will have the other half.

Dave

User
Posted 21 Jun 2022 at 08:11

I had my prostrate removed 2010.  psa readings since have been 0.01.  2021 reading was 4.00 this year 8.00.  Conclusion must be the covid jab.  Does anyone know why it has not been on the news?  Does anyone know any further information?

User
Posted 21 Jun 2022 at 08:51

Tolgate the COVID jab probably produces a temporary rise of a small value. Yours seems to be a big rise for a long time.

Is a medic monitoring this? If it is your GP they should have referred you to an oncologist when this rose above 0.1 . They probably didn't because those figures are reasonable for a man with a prostate in his 70s. They are not reasonable for a man who has had his prostate removed. If your GP refuses to refer you seek a second opinion, make sure everyone knows you do not have a prostate.

Dave

User
Posted 21 Jun 2022 at 09:05
Post hoc ergo propter hoc? The fact that your PSA has increased from 4 to 8 and you happen to have had the Covid vaccine certainly does not mean that the vaccine "must" be the cause of the increase. In fact I'd go so far as to say that it's vanishingly unlikely to be. The cause is (unfortunately) almost certainly that your cancer has returned. About 1 in 3 men who have an RP experience a recurrence of the cancer and go on to require salvage RT. Hopefully you have been referred to an oncologist?

Best wishes,

Chris

User
Posted 21 Jun 2022 at 09:40

I agree with Chris. This isn't due to a COVID jab.

As a prostatectomy patient, your max PSA would be a rising 0.1 or stable 0.2. Max temporary rise due to COVID that I've seen reported is 4x, and you are way outside that. Plus the COVID rise is temporary, but you have a doubling time of a year (depending on the exact timing), and you should be back under the care of oncology now.

User
Posted 21 Jun 2022 at 12:38

Tolgate, as said by others that rise needs to be checked out.

Guys, my PSA went from 0.38 to 0.62 after my first jab. It then dropped to 0.61 then went up to 0.73. it did drop from 1.0 to 0.99 after the booster jab. The second phase of the trial I was on proved inconclusive despite the first phase of the trial giving good results. The full report is awaited but I did wonder if the COVID jab was affecting the outcome. There was a set criteria for when to have the covid jab so a pattern may appear.

Thanks Chris 

User
Posted 21 Jun 2022 at 17:55

Spoke to doctor today and she is trying to fast track me for hospital.   Might be about a fortnight.

Tolly

User
Posted 21 Jun 2022 at 18:45

Glad to hear it, but you really should have been referred immediately when your PSA rose above 0.1. Someone's really dropped the ball big-time here 🙁.

Chris

 

User
Posted 12 Jul 2022 at 07:41

This is an update on my raised PSA.  The cancer has spread to my lungs,

User
Posted 12 Jul 2022 at 08:32
Very sorry to hear that. What treatment has been proposed? Chemo?

Best wishes,

Chris

User
Posted 12 Jul 2022 at 09:00
Sorry to hear that news Tollgate, I hope your oncologist is paying attention now.
User
Posted 12 Jul 2022 at 18:40

Well it is amazing that it stayed inactive for ten years, sadly it has reared its ugly head and I guess you will be back on the treatment band wagon. Hopefully it can be kept under control for a decade or so.

Dave

User
Posted 12 Jul 2022 at 19:10
Bri, how are you doing? Is your PSA behaving?
"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 02 Aug 2022 at 10:06

It has been non-stop since I first posted. I am following LHRH-agonist therapy. Tablets and injections.  See what it is like in 3 months.

 
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