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Veggie diet has benefits?

User
Posted 09 May 2024 at 19:36

Originally Posted by: Online Community Member

Lizzo,

Prostate Cancer UK have the following on their website which implies they see no problem with men on hormone treatment using Evening Primrose and presumably those men are having psa tests, although I wouldn't assume it:

'Herbal remedies use plants or plant extracts. Some men like to use herbal remedies, such as sage tea, evening primrose oil and red clover, to help with their hot flushes. But there's no evidence that these work, and it's important to check with your doctor that these are safe for you. For example, there is a small chance that a herbal supplement called black cohosh may cause liver damage. This is rare, but you shouldn't take it if you've ever had liver or kidney disease.'

Link below:

https://prostatecanceruk.org/prostate-information-and-support/living-with-prostate-cancer/how-hormone-therapy-affects-you

 

I can't find anything to support Andy's comment about psa being unsafely inhibited by 5ARI, as yet.   Although I have found articles saying 5ARI is found in many herbs, flax being one, but perhaps not much.

I'd never heard of any of this before 2 days ago.  I feel that if Evening Primrose was protective for pca we'd hear a lot more about it.   Although it does have benefits for hot flushes apparently.

 

This is a list of 5 alpha reductase inhibitors including herbal remedies 

In the herbal remedies it mentions  gamma linoleic acid - evening primrose oil is a major source of gamma linoleic acid 

https://en.wikipedia.org/wiki/List_of_5%CE%B1-reductase_inhibitors

 

User
Posted 10 May 2024 at 10:26

Originally Posted by: Online Community Member
I can't find anything to support Andy's comment about psa being unsafely inhibited by 5ARI, as yet. Although I have found articles saying 5ARI is found in many herbs, flax being one, but perhaps not much.

Loads of things act as 5ARIs to a minor extent, and there's no point in trying to avoid all those - you'd end up on a very weird/unbalanced diet. It's difficult to find out how much is in these, but if they're not used for reversing recent male pattern balding, there's probably too little to worry about.

The Finasteride dose used for enlarged prostate is 5mg/day, and this is the dose which halves your PSA.
The Finsateride dose used to treat male pattern hair loss is 1mg/day, and I don't know what impact that has on PSA (I don't know if the effect is linear, i.e. proportional to the dose).

Most of the foods/supplements containing 5ARI are not known for having any effect on male pattern hair loss, so I would guess their doses are much lower than the equivalent of even 1mg Finasteride. Saw Palmetto is a notable exception, in that it is effective enough to shrink the prostate and hair regrowth (at least in some formulations), although not as effective as Finsateride and Dutasteride. (Its formulations are also stupidly expensive, much more so that Finasteride and Dutasteride.)

Obviously, I can't assure you which foods/supplements containing 5ARI are safe to take without screwing up PSA readings, but ruling out everything containing small amounts is not viable, sensible, or useful.

User
Posted 10 May 2024 at 18:20

Originally Posted by: Online Community Member

Originally Posted by: Online Community Member
I can't find anything to support Andy's comment about psa being unsafely inhibited by 5ARI, as yet. Although I have found articles saying 5ARI is found in many herbs, flax being one, but perhaps not much.

Loads of things act as 5ARIs to a minor extent, and there's no point in trying to avoid all those - you'd end up on a very weird/unbalanced diet. It's difficult to find out how much is in these, but if they're not used for reversing recent male pattern balding, there's probably too little to worry about.

The Finasteride dose used for enlarged prostate is 5mg/day, and this is the dose which halves your PSA.
The Finsateride dose used to treat male pattern hair loss is 1mg/day, and I don't know what impact that has on PSA (I don't know if the effect is linear, i.e. proportional to the dose).

Most of the foods/supplements containing 5ARI are not known for having any effect on male pattern hair loss, so I would guess their doses are much lower than the equivalent of even 1mg Finasteride. Saw Palmetto is a notable exception, in that it is effective enough to shrink the prostate and hair regrowth (at least in some formulations), although not as effective as Finsateride and Dutasteride. (Its formulations are also stupidly expensive, much more so that Finasteride and Dutasteride.)

Obviously, I can't assure you which foods/supplements containing 5ARI are safe to take without screwing up PSA readings, but ruling out everything containing small amounts is not viable, sensible, or useful.

 

 

Why would any adult  avoid 5alpha reductase inhibitor food sources  in their diet ? 

Biotin  vitamin b7 is the biggest booster of hair growth I have ever come across I have searched for  research linking biotin to prostate cancer prevention bc it is obvs a major  DHT inhibitor the only caveat is Biotin affects blood tests so dont take it for a few days before any  blood test 

it is an amazing vitamin 

Btw in UK US Europe etc there is very little research into cancer 

Edited by member 10 May 2024 at 18:33  | Reason: Typo

User
Posted 10 May 2024 at 19:56

Originally Posted by: Online Community Member

Why would any adult  avoid 5alpha reductase inhibitor food sources  in their diet ?

Only because of the possibility of generating misleading PSA results, but this would only be with significant doses of 5ARIs.

Originally Posted by: Online Community Member
Biotin  vitamin b7 is the biggest booster of hair growth I have ever come across I have searched for  research linking biotin to prostate cancer prevention bc it is obvs a major  DHT inhibitor the only caveat is Biotin affects blood tests so dont take it for a few days before any  blood test

It takes around 6 months for PSA to stabilise after loss of androgens, and 12 months after restoration of androgens. A few days won't do anything.

As already mentioned, inhibiting DHT has no impact on prostate cancer, only PSA. (There is some thought it might reduce the chance of getting prostate cancer in the first place, but that ship already sailed.) As far as I can see, Biotin is not a 5ARI, but it is sometimes taken with Finasteride to promote hair growth (Finasteride being a 5ARI which is used to prevent male pattern baldness, amongst other things).

User
Posted 10 May 2024 at 20:47

Originally Posted by: Online Community Member

Originally Posted by: Online Community Member

Why would any adult  avoid 5alpha reductase inhibitor food sources  in their diet ?

Only because of the possibility of generating misleading PSA results, but this would only be with significant doses of 5ARIs.

Originally Posted by: Online Community Member
Biotin  vitamin b7 is the biggest booster of hair growth I have ever come across I have searched for  research linking biotin to prostate cancer prevention bc it is obvs a major  DHT inhibitor the only caveat is Biotin affects blood tests so dont take it for a few days before any  blood test

It takes around 6 months for PSA to stabilise after loss of androgens, and 12 months after restoration of androgens. A few days won't do anything.

As already mentioned, inhibiting DHT has no impact on prostate cancer, only PSA. (There is some thought it might reduce the chance of getting prostate cancer in the first place, but that ship already sailed.) As far as I can see, Biotin is not a 5ARI, but it is sometimes taken with Finasteride to promote hair growth (Finasteride being a 5ARI which is used to prevent male pattern baldness, amongst other things).

 as I said before biotin is amazing for hair growth and has many other  benefits yet it  is only lauded for optimising  pharma drug  absorption there is no scientific data on its powerful dht blocking ability except by male pattern balding remedy companies 

 

 
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