Hi mate.
I use https://www.mskcc.org/nomograms/prostate
It covers extra prostatic extension, positive margins, pre-op and post-op PSA levels. It also takes into account how long your PSA has remained undetectable since the op.
It states in the mskcc nonogram . "In general, the longer one remains free of recurrence following surgery, the more favorable one’s likelihood of continuing to remain recurrence-free."
Did you manage to add this particular factor into your AI calculation?
It's been over two years, since my op, touchwood, my PSA has remained undetectable. I was T3a, Gleason 9(4+5) with EPE but was lucky and had negative margins. My estimated chances of being BCR free appear to be after 5 years, 66%, after five years, 55% and after I0 years at 42%
It is important to note when using the mskcc nonogram for post operative results, that their probability is based on your likelihood of remaining BCR free not the chances of getting BCR.
Gradually, I've become less anxious about the chances of BCR. I'm trying to concentrate more on the present, and being 'cancer free', rather than trying to predict whether or not it'll return.
Like you I'm in favour of AI. At present, it seems to me that, the accuracy of biopsies and the interpretation of the results (the Gleason score) are two of the most important factors in diagnosing and treating PCa. Both are open to human error and interpretation. Perhaps AI would be more accurate?
One of my sons is a bioinformatician working in genetic research. He says, that AI is being increasingly used to good effect. In fact, he reckons it's so good, that he'll probably be made redundant within a couple of years. 🙁
Edited by member 10 May 2025 at 08:57
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